Cortexin vs Selank
Research Verdict
Neither compound has a universal evidence advantage. Both peptides serve distinct research goals with comparable evidence; choose by target mechanism.
Quick Answers
Which is better, Cortexin or Selank?
Neither compound has a universal evidence advantage. Both peptides serve distinct research goals with comparable evidence; choose by target mechanism.
What is the key difference between Cortexin and Selank?
Selank is a single defined molecule with known GABA/serotonin mechanism; cortexin is a mixture of unknown peptides - selank is scientifically reproducible, cortexin is not.
Evidence Comparison
Selank: defined synthetic peptide (tuftsin analog), Russian RCT data (Semenova 2010, n=38), approved in Russia. Cortexin: bovine brain extract, Russian clinical studies but no controlled RCTs meeting Western standards. Selank has stronger evidence quality per-study.
Evidence Context Favoring Cortexin
Russian clinical contexts where cortexin is prescribed for broad neuroprotection.
Evidence Context Favoring Selank
Anxiolytic-cognitive research requiring a defined molecule with characterized pharmacology and controlled trial data.
Side-by-Side Snapshot
| Evidence grade | Cortexin: Level C Selank: Level C |
|---|---|
| Research status | Cortexin: Approved Outside US Selank: Approved Outside US |
| Primary category | Cortexin: Cognitive & Nootropic Selank: Cognitive & Nootropic |
| Cited studies | Cortexin: 2 Selank: 2 |